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| Product Name | Succinyl-CoA Synthatase Activity Colorimetric BioAssay™ Kit (SCS, Succinyl-CoA Ligase, Succinate Thiokinase) |
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| Description | Succinyl-CoA Synthetase (SCS, also called Succinyl-CoA ligase, Succinate Thiokinase) (EC 6.2.1.5) is a critical enzyme in the citric acid cycle and an important metabolic intermediate for porphyrin, heme and ketone body biosynthesis. It is located in the mitochondrial matrix and is a heterodimer composed of one alpha and one beta subunit. In humans, Succinyl-CoA Synthetase deficiency causes the build-up of lactic acid leading to lactic acidosis, which can be fatal in infants. Measurement and analysis of SCS activity is useful for both mechanistic studies as well as for diagnostic purposes. Sample Type: Animal tissues: heart, liver, muscle, etc. Cell culture: adherent or suspension cells. Purified mitochondria. Intended Use: For use in the measurement of Succinyl-CoA Synthetase activity in various tissues/cells and for analysis of the cell signaling pathway. Sensitivity: This kit can detect <0.1mU of Succinyl-CoA Synthetase activity in a variety of samples. Test Principle: In the Succin |
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| Size | 100 tests |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | n/a |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | 220289 |
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| Order / More Info | Succinyl-CoA Synthatase Activity Colorimetric BioAssay™ Kit (SCS, Succinyl-CoA Ligase, Succinate Thiokinase) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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