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| Product Name | NQO1, Recombinant, Human, aa1-274, His-tag |
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| Description | Purity ~90% (SDS-PAGE). NQO1 is a cytosolic antioxidant flavoprotein that catalyzes the reduction of highly reactive quinone metabolites and their derivatives by using NAD (P)H as an electron donor. Thus NQO1 acts as a detoxifying enzyme and is involved in the body's protection against oxidative stress. NQO1 acts as a protein chaperone, one of its targets being p53. In humans NQO1 is expressed at high levels in adipocytes and its expression levels are positively correlated with adiposity, glucose tolerance, and makers of liver dysfunction. Altered expression of NQO1 is associated with Alzheimer's disease. NQO1 is abnormally elevated in many types of solid tumors and may represent a useful biomarker of pancreatic cancer. Source: Recombinant protein corresponding to aa1-274 of human NQO1, fused to His-tag at C-terminal expressed in E. coli. Molecular Weight: ~30kD Endotoxin: <0.1EU/ug (LAL method) |
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| Size | 10ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | NQO1, Recombinant, Human, aa1-274, His-Tag (NAD(P)H Dehydrogenase (Quinine) 1 (NQO1), Quinone Reductase 1 (QR1), DT-Diaphorase (DTD), Azoreductase, Phylloquinone Reductase, Menadione Reductase, Dioxin-inducible 1, Disphorase-4 (DIA4), NAD(P)H Quinone Oxireductase, Quinone Oxidoreductase 1) |
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| Gene, Accession, CAS # | NQO1, Gene ID: 1728, SwissProt: P15559 |
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| Catalog # | 301258 |
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| Order / More Info | NQO1, Recombinant, Human, aa1-274, His-tag from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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