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| Product Name | PKC iota, Recombinant, Human, GST-Tag (PRKCI, Protein Kinase C iota Type, DXS1179E, nPKC-iota) |
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| Description | Purified (~70-90%). PKC is a member of the protein kinase C family of serine-threonine kinases. The amino acid sequence of PKC showed greatest homology to PKCzeta, with 72% identity overall rising to 84% in the catalytic domain. Protein kinase C iota (PKC) has been implicated in Ras signaling and is a critical downstream effector of oncogenic Ras in the colonic epithelium. Transgenic mice expressing constitutively active PKC in the colon are highly susceptible to carcinogen-induced colon carcinogenesis. Source: Recombinant protein corresponding to human PKC iota, fused to GST-Tag at N-terminal expressed in Insect cells. Molecular Weight: ~98kD Specific Activity: 664nmol/min/mg as per activity assay protocol. Endotoxin: <1EU/ug (LAL) |
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| Size | 10ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | n/a |
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| Gene, Accession, CAS # | Accession: NM_002740 |
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| Catalog # | 500392 |
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| Order / More Info | PKC iota, Recombinant, Human, GST-Tag (PRKCI, Protein Kinase C iota Type, DXS1179E, nPKC-iota) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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