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| Product Name | GAB1 Recombinant protein |
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| Description | MW: ~108 kDa. Recombinant full-length human GAB1 was expressed by baculovirus in Sf9 insect cells using an N-terminal His tag.Scientific Background: GAB1 is a member of the IRS1-like multisubstrate docking protein family and is a direct substrate of the epidermal growth factor receptor and the insulin receptor (1). GAB1 is tyrosine phosphorylated upon stimulation of cells with various cytokines, growth factors, and antigen receptor. Tyrosine phosphorylation of GAB1 mediates intera |
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| Size | 0.02 mg, 0.05 mg |
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| Concentration | n/a |
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| Applications | Western Blot (WB) |
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| Other Names | [Homo sapiens GRB2-associated binding protein 1 (GAB1), transcript variant 1, mRNA; GRB2-associated-binding protein 1; GRB2-associated-binding protein 1; GRB2-associated binder 1; growth factor receptor bound protein 2-associated protein 1; GRB2-associated binding protein 1; GRB2-associated binder 1; Growth factor receptor bound protein 2-associated protein 1] |
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| Gene, Accession, CAS # | GAB1, Gene ID: 2549, Accession: NP_997006.1 |
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| Catalog # | MBS515364 |
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| Order / More Info | GAB1 Recombinant protein from MYBIOSOURCE INC. |
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| Product Specific References | 1.Holgado-Madruga M, et al: A Grb2-associated docking protein in EGF- and insulin-receptor signalling. Nature 379: 560-564, 1996. 2.Kiyatkin A, et al: Scaffolding protein Grb2-associated binder 1 sustains epidermal growth factor-induced mitogenic and survival signaling by multiple positive feedback loops. J Biol Chem. 2006 Jul 21;281(29):19925-38. |
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