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| Product Name | CANT1, Recombinant, Human |
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| Description | Purity ~95% (SDS-PAGE). Calcium Activated Nucleotidase 1 (CANT1), is a Ca2+-dependent nucleoside diphosphatase which can hydrolyze a variety of nucleoside di- and triphosphates. CANT1 is also known as SCAN-1 and SHAPY. Its preferred substrates are UDP and GDP, and it is not active against nucleoside monophosphates (1). The CANT1 gene encodes a Type II membrane protein that is anchored in the endoplasmic reticulum (ER) membrane with its catalytic domain in the ER lumen (2). A secreted, soluble form of the enzyme also exists (1). CANT1 is expressed in many tissues, including fibroblasts and chondrocytes. Mutations of CANT1 are a cause of Desbuquois dysplasia, a condition characterized by deformation of bones and joints (2, 3). Recombinant human CANT1 was expressed as a secreted, soluble protein. Source: Recombinant corresponding to aa80-401 from human CANT1, fused with 6-His tag at N-terminal, expressed in NS0 cells. Molecular Weight: ~37kD Biological Activity: Measured by its ability to |
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| Size | 10ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | CANT1, Recombinant, Human (Putative NF-kappa-B-activating Protein 107, Putative MAPK-activating Protein PM09, Apyrase Homolog, Soluble Calcium-activated Nucleotidase 1, SCAN-1, SHAPY) |
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| Gene, Accession, CAS # | SwissProt: Q8WVQ1 |
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| Catalog # | C1075-78C |
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| Order / More Info | CANT1, Recombinant, Human from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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