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| Product Name | Recombinant Human Cellular tumor antigen p53 |
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| Description | 1-393aa; Full Length. MW: 59.49kD. Purity >90% as determined by SDS-PAGE. Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction ses to be mediated either by sti |
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| Size | 0.01 mg (Yeast), 0.01 mg (E-Coli), 0.05 mg (Yeast), 0.05 mg (E-Coli), 0.1 mg (E-Coli) |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | [Antigen NY-CO-13; Phosphoprotein p53; Tumor suppressor p53] |
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| Gene, Accession, CAS # | TP53, Gene ID: 7157, Accession: NP_000537.3 |
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| Catalog # | MBS968568 |
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| Order / More Info | Recombinant Human Cellular tumor antigen p53 from MYBIOSOURCE INC. |
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| Product Specific References | Human p53 cellular tumor antigencDNA sequence and expression in COS cells.Zakut-Houri R., Bienz-Tadmor B., Givol D., Oren M.EMBO J. 4:1251-1255(1985) Characterization of the human p53 gene.Lamb P., Crawford L.Mol. Cell. Biol. 6:1379-1385(1986) Molecular cloning and in vitro expression of a cDNA clone for human cellular tumor antigen p53.Harlow E., Williamson N.M., Ralston R., Helfman D.M., Adams T.E.Mol. Cell. Biol. 5:1601-1610(1985) Molecular basis for heterogeneity of the human p53 protein.Har |
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