| 产品详情 |
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| Product Name | VPC 23019 |
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| Description | Purity >95%. Sphingosine-1-phosphate (S1P) is a bioactive lipid that exhibits a broad spectrum of biological activities including cell proliferation, survival, migration, cytoskeletal organization, and morphogenesis. It exerts its activity by binding to five distinct G protein-coupled receptors, S1P1 /EDG-1, S1P2 /EDG-5, S1P3 /EDG-3, S1P4 /EDG-6, and S1P5 /EDG-8. VPC 23019 is an aryl amide-containing S1P analog that acts as a competitive antagonist at both S1P1 and S1P3 receptors (pKi s = 7.86 and 5.93, respectively). It can inhibit S1P-induced migration of thyroid cancer cells, ovarian cancer cells, and neural stem cells. |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | (R)-2-amino-3-((3-octylphenyl)amino)-3-oxopropyl dihydrogen phosphate |
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| Gene, Accession, CAS # | CAS: 449173-19-7 |
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| Catalog # | LS-H10456 |
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| Price | |
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| Order / More Info | VPC 23019 from LIFESPAN BIOSCIENCES INC. |
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| Product Specific References | n/a |
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| 产品资料 |
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