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| Product Name | AOX1 AO, Recombinant, Human, aa236-421, His-Tag (Aldehyde Oxidase) |
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| Description | Purity ~85% (SDS-PAGE). Oxidase with broad substrate specificity, oxidizing aromatic azaheterocycles, such as N1-methylnicotinamide and N-methylphthalazinium, as well as aldehydes, such as benzaldehyde, retinal, pyridoxal, and vanillin. Plays a key role in the metabolism of xenobiotics and drugs containing aromatic azaheterocyclic substituents. Participates in the bioactivation of prodrugs such as famciclovir, catalyzing the oxidation step from 6-deoxypenciclovir to penciclovir, which is a potent antiviral agent. Is probably involved in the regulation of reactive oxygen species homeostasis. May be a prominent source of superoxide generation via the one-electron reduction of molecular oxygen. Also may catalyze nitric oxide (NO) production via the reduction of nitrite to NO with NADH or aldehyde as electron donor. May play a role in adipogenesis. Source: Recombinant protein corresponding to aa236-421 from human Aldehyde oxidase, fused to His-Tag at N-terminal, expressed in E. coli. Molecular Weight: ~24.7kD AA |
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| Size | 10ug, 50ug, 100ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | AIdehyde Oxidase 1, Azaheterocycle Hydroxylase (EC:1.17.3.-) |
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| Gene, Accession, CAS # | SwissProt: Q06278 |
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| Catalog # | 372278 |
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| Order / More Info | AOX1 AO, Recombinant, Human, aa236-421, His-Tag (Aldehyde Oxidase) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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