| 产品详情 |
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| Product Name | Borrelidin (Treponemycin, U 78548, C2989) |
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| Description | Purity ~98% (HPLC). Macrolide antibiotic. Bacterial and eukaryal threonyl-tRNA synthetase (THrRS) inhibitor. Antiangiogenic (IC50=0.8nM). Induces the collapse of formed capillary tubes in a dose-dependent fashion. In HUVECs, the capillary tube collapsing activity is mediated by the activation of caspases-3 and -8 and induction of apoptosis. Blocks the formation of spontaneous lung metastases of B16-BL6 melanoma cells. Cyclin-dependent kinase (CDK) inhibitor. Antiviral. Antimalarial. Source: Streptomyces sp. Formula: C28H43NO6 Solubility: DMSO or methanol Molecular Weight: ~489.6 |
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| Size | 500ug, 1mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | n/a |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | 207093 |
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| Order / More Info | Borrelidin (Treponemycin, U 78548, C2989) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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| 产品资料 |
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