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| Product Name | MICB BioAssay™ ELISA Kit, Human |
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| Description | Sandwich ELISA quantitative detection kit for Human MICB in cell culture supernates, serum and plasma (heparin, EDTA). MHC class I polypeptide-related sequence B, also called MICB is a protein that in humans is encoded by the MICB gene. The MICB gene is mapped to 6p21.33. This gene encodes a heavily glycosylated protein which is a ligand for the NKG2D type II receptor. Binding of the ligand activates the cytolytic response of natural killer (NK) cells, CD8 alphabeta T cells, and gammadelta T cells which express the receptor. This protein is stress-induced and is similar to MHC class I molecules; however, it does not associate with beta-2-microglobulin or bind peptides. It seems to have no role in antigen presentation. This gene acts as a stress-induced self-antigen that is recognized by gamma delta T cells. It is the ligand for the KLRK1/NKG2D receptor and binds to KLRK1 leads to cell lysis. Assay Range: 62.5pg/ml-4000pg/ml Sensitivity: < 10 pg/ml Crossreactivity: There is no detectabl |
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| Size | 96 tests |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | n/a |
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| Gene, Accession, CAS # | Gene ID: 4277, SwissProt: Q29980 |
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| Catalog # | 143968 |
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| Order / More Info | MICB BioAssay™ ELISA Kit, Human from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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