| 产品详情 |
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| Product Name | SLK, Recombinant, Human, GST-tag |
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| Description | Purified (~70-90%). SLK or LOSK is a Ste20-like protein kinase that associates with microtubule and centrosome. Inhibition of SLK activity by dominant-negative mutant or RNAi leads to unfocused microtubule arrangement indicating that SLK is needed for microtubule organization and for the proper localization of Golgi complex. Expression of v-Src can down-regulate SLK activity through the involvement of CK2 which can directly phosphorylate and inhibit SLK activity whereas inhibition of CK2 in v-Src-transformed cells results in normal SLK activity. CK2 and SLK can be co-localized in fibroblasts spreading on fibronectin-coated substrates. Source: Recombinant protein corresponding to human SLK, fused to GST-Tag at N-terminal expressed in Insect cells. Molecular Weight: ~180kD Specific Activity: The specific activity of SLK was determined to be 4.6nmol/min/mg as per activity assay protocol. Endotoxin: <1EU/ug (LAL) |
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| Size | 10ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | SLK, Recombinant, Human, GST-Tag (STE20-Like Kinase, STE20-Like Serine/Threonine-Protein Kinase, LOSK, STK2, Se20-9, KIAA0204) |
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| Gene, Accession, CAS # | Accession: AB002804 |
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| Catalog # | 500451 |
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| Order / More Info | SLK, Recombinant, Human, GST-tag from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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