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| Product Name | ARHGEF7, Recombinant, Human, aa179-428, GST-Tag (Rho Guanine Nucleotide Exchange Factor 7) |
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| Description | Purity ~90% (SDS-PAGE). Acts as a RAC1 guanine nucleotide exchange factor (GEF) and can induce membrane ruffling. Functions in cell migration, attachment and cell spreading. Promotes targeting of RAC1 to focal adhesions. May function as a positive regulator of apoptosis. Downstream of NMDA receptors and CaMKK-CaMK1 signaling cascade, promotes the formation of spines and synapses in hippocampal neurons. 3 Publications. Source: Recombinant protein corresponding to aa179-428 from human ARHGEF7, fused to GST-Tag at N-terminal expressed in E. coli. Molecular Weight: ~55.3kD AA |
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| Size | 10ug, 50ug, 100ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | Beta-Pix COOL-1, PAK-interacting exchange factor beta p85 |
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| Gene, Accession, CAS # | SwissProt: Q14155 |
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| Catalog # | 372330 |
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| Order / More Info | ARHGEF7, Recombinant, Human, aa179-428, GST-Tag (Rho Guanine Nucleotide Exchange Factor 7) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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