| 产品详情 |
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| Product Name | Leukadherin-1 |
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| Description | Purity ~95% (HPLC). A furanyl thiazolidinone compound that binds CD11b aA/aI domain in a reversible manner and stabilizes aA in a high-affinity binding conformation toward known CD11b/CD18 (aMB2; CR3; Mac-1) ligands, fibrinogen, ICAM-1, and iC3B. Reported to be superior to IMB-10 in enhancing Mac-1-mediated cell adhesion (EC50=4 vs. >50uM on fibrinogen surface). Effectively suppresses leukocyte recruitment in various inflammatory disease models involving mice, rats, and zebrafish embryos in vivo. Formula: C22H15NO4S2 Molecular Weight: 421.5 Solubility: DMSO |
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| Size | 25mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | Leukadherin-1 (aMb2 Agonist II, CD11b Agonist II, LA1, Mac-1 Agonist II, CR3 Agonist II, CD11b/CD18 Agonist, 4-(5-((3-Benzyl-4-oxo-2-thioxo-1,3-thiazolidin-5-ylidene)methyl)furan-2-yl)-benzoic Acid) |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | 217511 |
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| Order / More Info | Leukadherin-1 from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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