| 产品详情 |
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| Product Name | CDK2/CyclinE1, Recombinant, Human, GST-Tag (CDK2: p33 (CDK2) CyclinE1: CCNE1, CCNE) |
| Description | Purified (~70-90%). CDK2 is a member of the Cyclin-Dependent Kinase family that is ubiquitously expressed. CDK2 is a catalytic subunit of the cyclin-dependent protein kinase complex, whose activity is restricted to the G1-S phase, and essential for cell cycle G1/S phase transition. CDK2 associates with and is regulated by the regulatory subunits of the complex including Cyclin A or E, CDK inhibitor p21Cip1 (CDKN1A) and p27Kip1 (CDKN1B). CDK2 phosphorylates multiple cellular substrates including SMAD3 and FOXO1. Phosphorylation of FOXO1 leads to its inhibition. Source: Recombinant protein corresponding to human CDK2/CyclinE1, fused to GST-Tag at N-terminal expressed in Insect cells. Molecular Weight: ~58kD, 73kD Specific Activity: 404nmol/min/mg as per activity assay protocol. Endotoxin: <1EU/ug (LAL) |
| Size | 10ug |
| Concentration | n/a |
| Applications | n/a |
| Other Names | n/a |
| Gene, Accession, CAS # | Accession: NM_001798 |
| Catalog # | 499869 |
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| Order / More Info | CDK2/CyclinE1, Recombinant, Human, GST-Tag (CDK2: p33 (CDK2) CyclinE1: CCNE1, CCNE) from UNITED STATES BIOLOGICAL |
| Product Specific References | n/a |
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