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| Product Name | Flagellin, S. typhimurium (FlaF, Hag) |
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| Description | Purity ~95% (SDS-PAGE). Flagellin is a protein (495aa, 30-60kD, refs 1) that arranges itself in a hollow cylinder to form the filament in bacterial flagellum. Individual Salmonella serotypes usually alternate between the production of 2 antigenic forms of flagella, termed phase 1 and phase 2, each specified by separate structural genes, fliC and fljB. Flagellin is the principal protein of bacterial flagellum, and is present in large amounts on nearly all flagellated bacteria. It confers motility on a wide range of bacterial species. Flagellin is a potent stimulator of innate immune responses in a number of eukaryotic cells and organisms, including both mammals and plants. In mammals, flagellin is recognized by TLR51 and triggers defense responses both systemically and at epithelial surfaces. Flagellin induces the activation of NF-kappaB and the production of cytokines and nitric oxide depending on the nature of the TLR5 signaling complex. The structure of flagellin is responsible for t |
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| Size | 50ug |
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| Concentration | n/a |
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| Applications | ELISA WB |
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| Other Names | n/a |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | 208902 |
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| Order / More Info | Flagellin, S. typhimurium (FlaF, Hag) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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