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| Product Name | PLTP, Recombinant, Mouse (Phospholipid Transfer Protein) |
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| Description | Purity ≥95% (SDS-PAGE). Endotoxin: ≤1.0 EU/1ug (LAL). . Mouse PLTP Phospholipid transfer protein (PLTP; also lipid transfer protein II) is an 80kD, secreted glycoprotein, that belongs to the BPI/LBP/Plunc superfamily, BPI/LBP family of molecules (1). It is synthesized as a precursor with a 17aa signal sequence and a 476aa mature chain (SwissProt # P55065). The mature chain contains two BPI/LBP/CETP domains (aa21-239 and 263-463) and seven potential sites for N-linked glycosylation. Mature mouse PLTP shares 83% aa sequence identity with mature human PLTP (3). PLTP is expressed by a wide variety of tissues and is secreted by macrophages. Northern blot analysis shows the order of PLTP mRNA expression as follows: lung > adipose tissue, placenta, testis > brain > muscle, heart, liver (2). PLTP is a multifunctional, extracellular lipid transfer protein that plays a major role in lipoprotein metabolism and atherosclerosis (4-6). In addition to phospholipids, PLTP transfers several amphipatic |
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| Size | 25ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | n/a |
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| Gene, Accession, CAS # | Accession: AAH03782 |
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| Catalog # | P4278-01 |
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| Order / More Info | PLTP, Recombinant, Mouse (Phospholipid Transfer Protein) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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