产品名称 CSTB, Recombinant, Human, aa1-98, His-Tag(Cystatin-B, Stefin B, PME, CST6) from UNITED STATES BIOLOGICAL
产品货号 351169
产品价格 现货询价,电话:010-67529703
产品规格 10ug, 50ug
产品品牌 UNITED STATES BIOLOGICAL
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Product NameCSTB, Recombinant, Human, aa1-98, His-Tag(Cystatin-B, Stefin B, PME, CST6)
DescriptionPurity ~95% (SDS-PAGE). CSTB, also known as Cystatin B is an anti-protease implicated in myoclonus epilepsy, a degenerative disease of the central nervous system. The cystatin superfamily encompasses proteins that contain multiple cystatin- like sequences. Some of the members are active cysteine protease inhibitors, while others have lost or perhaps never acquired this inhibitory activity. This protein is able to form a dimer stabilized by noncovalent forces and is thought to play a role in protecting against the proteases leaking from lysosomes. In cells, CSTB is located in the lysosomes and the cytoplasm, but also in the nucleus. Source: Recombinant protein corresponding to aa1-98 from human CSTB, fused to His-tag expressed in E. coli. Molecular Weight: ~13kD (118aa) Biological Activity: The IC50 value is <3nM. The inhibitory function of Cystatin B on protease activity of papain was measured by a fluorometric assay using Z-FR-AMC at pH 7.5 at 25°C. AA
Size10ug, 50ug
Concentrationn/a
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Gene, Accession, CAS #Accession: NP_000091
Catalog #351169
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Order / More InfoCSTB, Recombinant, Human, aa1-98, His-Tag(Cystatin-B, Stefin B, PME, CST6) from UNITED STATES BIOLOGICAL
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