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| Product Name | Trichostatin A (TSA) (Histone Deacetylase Inhibitor) |
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| Description | Highly Purified (≥ 99% by HPLC). Trichostatin A is an antifungal antibiotic that is a reversible, potent and specific inhibitor of mammalian histone deacetylase (HDAC) both in vivo and in vitro. Histone deacetylase inhibition causes chromatin relaxation and gene expression modulation. May induce apoptosis. TSA inhibits the eukaryotic cell cycle and induces morphological reversion of transformed cells. It blocks cell cycle progression at G1 phase in Hela Cells. TSA causes accumulation of highly acetylated histones in vivo, while inhibiting the activity of partially purified histone deacetylase in vitro. Applications: Suitable for use in Inhibition of Histone Deacetylation. |
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| Size | 1mg, 5mg |
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| Concentration | n/a |
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| Applications | N |
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| Other Names | 4,6-Dimethyl-7-[p-dimethylaminophenyl]- 7-oxohepta-2, 4-dienohydroxamic acid) |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | T8375-05 |
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| Order / More Info | Trichostatin A (TSA) (Histone Deacetylase Inhibitor) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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