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| Product Name | GZMB, Recombinant, Human, aa19-247, His-tag |
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| Description | Purity ~95% (SDS-PAGE). GZMB, also known as granzyme B isoform 1, is member of the granzyme subfamily of proteins, part of the peptidase S1 family of serine proteases. Tis protein is secreted by natural killer (NK) cells and cytotoxic T lymphocytes (CTLs) and proteolytically processed to generate the active protease, which induces target cell apoptosis. Also, it processes cytokines and degrades extracellular matrix proteins, and these roles are implicated in chronic inflammation and wound healing. Expression of this gene may be elevated in human patients with cardiac fibrosis. Recombinant human GZMB, fused to His-Tag at C-terminal, expressed in insect cell and purified by using conventional chromatography techniques. Source: Recombinant protein corresponding to aa19-247 of human GZMB, fused to His-Tag at C-terminal, expressed in insect cell. Molecular Weight: ~26.5kD (235aa), ~28-40kD (SDS-PAGE under reducing conditions.) Endotoxin: <1EU/1ug (determined by LAL method) AA |
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| Size | 5ug, 20ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | GZMB, Recombinant, Human, aa19-247, His-Tag (Granzyme B Isoform 1, GZMB, C11, CCPI, CGL-1, CGL1, CSP-B, CSPB, CTLA1, CTSGL1, HLP, SECT) |
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| Gene, Accession, CAS # | Accession: NP_004122 |
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| Catalog # | 396872 |
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| Order / More Info | GZMB, Recombinant, Human, aa19-247, His-tag from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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