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| Product Name | Human NANOG Protein (Recombinant) |
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| Description | Purity >95% by non-reducing SDS-PAGE and HPLC, MW: 36.2 kDa (SDS-PAGE). NANOG is a transcription factor involved with self-renewal of inner cell mass and embryonic stem (ES) cells by functioning in concert with other factors such as POU5F1 (Oct-4) and SOX2. Nanog imposes pluripotency on ES cells and prevents their differentiation towards extraembryonic endoderm and trophectoderm lineages, and blocks bone morphogenetic protein-induced mesoderm differentiation of ES cells by physically interacting with SMAD1 and interfering with the recruitment of coactivators to the active SMAD transcriptional complexes.Recombinant human NANOG-TAT (rhNANOG-TAT) produced in E. coli is a single chain, 318 amino acids non-glycosylated polypeptide. A fully biologically active molecule, rhNANOG-TAT has a molecular mass of 36.2 kDa analyzed by reducing SDS-PAGE and is obtained by chromatographic techniques. |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | NANOG, Nanog homeobox, NANOGP8, HNanog, Homeobox protein NANOG |
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| Gene, Accession, CAS # | NANOG, Gene ID: 79923 |
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| Catalog # | LS-G27084 |
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| Order / More Info | Human NANOG Protein (Recombinant) from LIFESPAN BIOSCIENCES INC. |
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| Product Specific References | n/a |
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