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| Product Name | Ras R2, Recombinant, Human (RAS viral (r-ras) oncogene homolog 2, RRAS2) |
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| Description | Purity ~95% (SDS-PAGE) Purified by immunoaffinity chromatography. RAS viral (r-ras) oncogene homolog 2 isoform a, also known as RRAS2, belongs to the Ras like GTPase family that cycle between GTP-bound active and GDP-bound inactive states at the cytoplasmic face of the plasma membrane. It is implicated in the pathogenesis of human cancers. Thus, overexpression of active RRAS2 in EpH4 cells induces tumorigenicity through the phosphoinositide 3-kinase, p38 MAPK, and mTOR pathways, and these cells lose their sensitivity to the normal growth inhibitory role of TGF-beta. Recombinant human RRAS2, fused to His-tag at N-terminus, , expressed in E. coli and purified by using conventional chromatography techniques. Source: Recombinant corresponding to human RRAS2, aa1- 201, his-tagged, expressed in E. coli. AA Sequence: MGSSHHHHHH SSGLVPRGSH MAAAGWRDGS GQEKYRLVVV GGGGVGKSAL TIQFIQSYFV TDYDPTIEDS YTKQCVIDDR AARLDILDTA GQEEFGAMRE QYMRTGEGFL LVFSVTDRGS FEEIYKFQRQ ILRVKDRDEF PMILIGNKAD LDHQRQVTQE E |
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| Size | 100ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | n/a |
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| Gene, Accession, CAS # | Accession: NP_036382 |
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| Catalog # | R1200-10G |
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| Order / More Info | Ras R2, Recombinant, Human (RAS viral (r-ras) oncogene homolog 2, RRAS2) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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