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| Product Name | Transforming Growth Factor beta1, Recombinant, Human, active |
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| Description | Purity ≥98% by SDS-PAGE and HPLC Endotoxin: ≤0.1ng/ug (1EU/ug). The three mammalian isoforms of TGF-beta, TGF-beta1, beta2, beta3, signal through the same receptor and elicit similar biological responses. They are multifunctional cytokines that regulate cell proliferation, growth, differentiation and motility as well as synthesis and deposition of the extracellular matrix. They are involved in various physiological processes including embryogenesis, tissue remodeling and would healing. They are secreted predominantly as latent complexes which are stored at the cell surface and in the extracellular matrix. The release of biologically active TGF-beta isoform from a latent complex involves proteolytic processing of the complex and /or induction of conformational changes by proteins such as thrombospondin-1. TGF-beta1 is the most abundant isoform secreted by almost every cell type. It was originally identified for its ability to induce phenotypic transformation of fibroblasts and recently |
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| Size | 2ug, 10ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | Transforming Growth Factor beta1, Recombinant, Human, active (TGF beta 1, TGFb1, Camurati Engelmann Disease, CED, Diaphyseal Dysplasia 1 Progressive, DPD1, TGFb1, Differentiation Inhibiting Factor, Cartilage-inducing Factor) |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | T8250-15A |
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| Order / More Info | Transforming Growth Factor beta1, Recombinant, Human, active from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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