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| Product Name | Transforming Growth Factor beta2, Recombinant, Human (TGF b2) |
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| Description | Highly purified (~ 98% by SDS-PAGE and HPLC)Endotoxin: ≤0.1ng/ug (1EU/ug). The three mammalian isoforms of TGF-beta, TGF-beta1, TGF-beta2, TGF-beta3, signal through the same receptor and elicit similar biological responses. They are multifunctional cytokines that regulate cell proliferation, growth, differentiation, motility and synthesis and deposition of the extracellular matrix. They are involved in various physiological processes including embryogenesis, tissue remodeling and would healing. They are secreted predominantly as latent complexes which are stored at the cell surface and in the extracellular matrix. The release of biologically active TGF-beta isoform from a latent complex involves proteolytic processing of the complex and/or induction of conformational changes by proteins such as thrombospondin-1. TGF-beta2 has been shown to exert suppressive effects on IL-2 dependent T-cell growth. It may also have an autocrine function in enhancing tumor growth by suppressing immuno-s |
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| Size | 2ug, 10ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | n/a |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | T8251 |
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| Order / More Info | Transforming Growth Factor beta2, Recombinant, Human (TGF b2) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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