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| Product Name | Nanog, Recombinant, Human, aa1-305 |
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| Description | Purity ~90% (SDS-PAGE). Nanog homeobox, also known as nanog, is a member of the homeobox family of DNA binding transcription factors that has been shown to maintain pluripotency of embryonic stem cells. Nanog expression counteracts the differentiation-promoting signals induced by the extrinsic factors LIF, Stat3 and BMP. Once NANOG expression is downregulated, cell differentiation can proceed. Proteins which regulate NANOG expression include transcription factors Oct4, SOX2, FoxD3, and Tcf3 and tumor suppressor p53. Source: Recombinant corresponding to aa1-305 of human Nanog, expressed in E.coli. AA sequence: MSVDPACPQS LPCFEASDCK ESSPMPVICG PEENYPSLQM SSAEMPHTET VSPLPSSMDL LIQDSPDSST SPKGKQPTSA EKSVAKKEDK VPVKKQKTRT VFSSTQLCVL NDRFQRQKYL SLQQMQELSN ILNLSYKQVK TWFQNQRMKS KRWQKNNWPK NSNGVTQKAS APTYPSLYSS YHQGCLVNPT GNLPMWSNQT WNNSTWSNQT QNIQSWSNHS WNTQTWCTQS WNNQAWNSPF YNCGEESLQS CMQFQPNSPA SDLEAALEAA GEGLNVIQQT TRYFSTPQTM DLFLNYSMNM QPEDV Molecular Weight: ~34.6kD (305aa) |
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| Size | 100ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | Nanog, Recombinant, Human, aa1-305 (Early Embryo Specific Expression NK Family Gene, Embryonic Stem Cell Specific Homeobox Protein, ENK, FLJ12581, FLJ40451, Homeobox Transcription Factor Nanog, Nanog Homeobox) |
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| Gene, Accession, CAS # | Accession: NP_079141 |
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| Catalog # | N0019-01Z |
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| Order / More Info | Nanog, Recombinant, Human, aa1-305 from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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