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| Product Name | Nanog, Recombinant, Human (Homeobox Transcription Factor Nanog) |
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| Description | Purity ~98% (SDS-PAGE). Nanog is a regulatory protein that is associated with undifferentiated pluripotent cells. The expression of Nanog, which is suppressed in all adult tissues, is restricted to embryonic stem cells and to certain pluripotent cancer cells. Decreased expression of Nanog is strongly correlated with cell differentiation. Nanog, most likely, acts as an intracellular regulator, which maintains pluripotency and self-renewal via a STAT3 independent pathway. Recombinant human Nanog is synthesized as a 304aa polypeptide lacking a signal sequence for secretion. Source: Recombinant protein corresponding to 304aa from human Nanog, expressed in E. coli. Molecular Weight: ~34.7kD Endotoxin: <0.1ng/ug of protein (<1EU/ug) AA Sequence: SVDPACPQSL PCFEASDCKE SSPMPVICGP EENYPSLQMS SAEMPHTETV SPLPSSMDLL IQDSPDSSTS PKGKQPTSAE NSVAKKEDKV PVKKQKTRTV FSSTQLCVLN DRFQRQKYLS LQQMQELSNI LNLSYKQVKT WFQNQRMKSK RWQKNNWPKN SNGVTQKASA PTYPSLYSSY HQGCLVNPTG NLPMWSNQTW NNSTWSNQTQ NIQSWSNHSW NTQTWCTQ |
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| Size | 10ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | Homeobox transcription factor Nanog |
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| Gene, Accession, CAS # | Nanog, Gene ID: 79923, SwissProt: Q9H9S0 |
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| Catalog # | 220086 |
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| Order / More Info | Nanog, Recombinant, Human (Homeobox Transcription Factor Nanog) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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