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| Product Name | ENSA, Recombinant, Human, aa1-121, GST-Tag (Alpha-endosulfine) |
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| Description | Purity ~90% (SDS-PAGE). Protein phosphatase inhibitor that specifically inhibits protein phosphatase 2A (PP2A) during mitosis. When phosphorylated at Ser-67 during mitosis, specifically interacts with PPP2R2D (PR55-delta) and inhibits its activity, leading to inactivation of PP2A, an essential condition to keep cyclin-B1-CDK1 activity high during M phase. Also acts as a stimulator of insulin secretion by interacting with sulfonylurea receptor (ABCC8), thereby preventing sulfonylurea from binding to its receptor and reducing K(ATP) channel currents.1 Publication Source: Recombinant protein corresponding to aa1-121 from human ENSA, fused to GST-Tag at N-terminal expressed in E. coli. Molecular Weight: ~40.4kD AA |
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| Size | 10ug, 50ug, 100ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | ARPP-19e |
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| Gene, Accession, CAS # | SwissProt: O43768 |
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| Catalog # | 373186 |
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| Order / More Info | ENSA, Recombinant, Human, aa1-121, GST-Tag (Alpha-endosulfine) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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