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| Product Name | RORg Inverse Agonist, SR2211 |
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| Description | Purity ~99% (HPLC). A cell-permeable, piperazine containing biphenyl compound that binds directly to retinoic acid receptor related orphan receptor g (RORg) and acts as a highly selective and inverse agonist (Ki =105nM; IC50 ~320nM). Reported to block the transcriptional activity of RORg and suppress the synthesis of IL-17 in EL-4 murine lymphoma cell line. Exhibits only a minimal effect on RORa and LXRa activity. |
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| Size | 5mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | RORg Inverse Agonist, SR2211 (1,1,1,3,3,3-hexafluoro-2-(2-fluoro-4'-((4-(pyridin-4-ylmethyl)piperazin-1-yl)methyl)-[1,1'-biphenyl]-4-yl)propan-2-ol, SR-2211, SR 2211) |
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| Gene, Accession, CAS # | CAS: 1359164-11-6 |
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| Catalog # | 217753 |
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| Order / More Info | RORg Inverse Agonist, SR2211 from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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