| 产品详情 |
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| Product Name | Torcetrapib |
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| Description | Purity >98%. Torcetrapib is a cholesteryl ester transfer protein (CETP) inhibitor (IC50 = 37 nM). It raises high-density lipoprotein (HDL) cholesterol and reduces low-density lipoprotein (LDL) cholesterol levels. However, in clinical trials, Torcetrapib displayed unfavorable off-target effects in cardiovascular system. PDGFR, HGFR (c-Met), IL-2 receptor, and ErbB1- tyrosine kinase have subsequently been identified as direct off-targets of this compound. |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | (2R,4S)-ethyl 2-ethyl-4-(methoxycarbonyl)-6-(trifluoromethyl)-3,4-dihydroquinoline-1(2H)-carboxylate, CP 529414, CP529414, CP-529414 |
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| Gene, Accession, CAS # | CAS: 262352-17-0 |
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| Catalog # | LS-H2996 |
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| Price | |
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| Order / More Info | Torcetrapib from LIFESPAN BIOSCIENCES INC. |
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| Product Specific References | n/a |
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| 产品资料 |
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