| 产品详情 |
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| Product Name | PSME3, Recombinant, Human, aa2-252, GST-Tag (Proteasome Activator Complex Subunit 3) |
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| Description | Purity ~90% (SDS-PAGE). Subunit of the 11S REG-gamma (also called PA28-gamma) proteasome regulator, a doughnut-shaped homoheptamer which associates with the proteasome. 11S REG-gamma activates the trypsin-like catalytic subunit of the proteasome but inhibits the chymotrypsin-like and postglutamyl-preferring (PGPH) subunits. Facilitates the MDM2-p53/TP53 interaction which promotes ubiquitination- and MDM2-dependent proteasomal degradation of p53/TP53, limiting its accumulation and resulting in inhibited apoptosis after DNA damage. May also be involved in cell cycle regulation. Source: Recombinant protein corresponding to aa2-252 from human PSME3, fused to GST-Tag at N-terminal, expressed in E. coli. Molecular Weight: ~56.1kD AA |
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| Size | 10ug, 50ug, 100ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | 11S regulator complex subunit gamma, REG-gamma Activator of multicatalytic protease subunit 3Ki nuclear autoantigen, Proteasome activator 28 subunit gamma, PA28g, PA28 gamma |
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| Gene, Accession, CAS # | SwissProt: P61289 |
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| Catalog # | 374916 |
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| Order / More Info | PSME3, Recombinant, Human, aa2-252, GST-Tag (Proteasome Activator Complex Subunit 3) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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