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| Product Name | MBD3, Recombinant, Human, aa1-291, His-Tag (Methyl-CpG-binding Domain protein 3) |
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| Description | Purity ~85% (SDS-PAGE). Methyl-CpG-binding domain protein 3, also known as MBD3, is a member of the MBD family of transcriptional repressors. Human proteins MECP2, MBD1, MBD2, MBD3, and MBD4 comprise a family of nuclear proteins related by the presence in each of a methyl-CpG binding domain (MBD). However, unlike the other family members, MBD3 is not capable of binding to methylated DNA. The predicted MBD3 protein shares 71% and 94% identity with MBD2 (isoform 1) and mouse Mbd3. MBD3 is a subunit of the NuRD, a multisubunit complex containing nucleosome remodeling and histone deacetylase activities. MBD3 mediates the association of metastasis-associated protein 2 (MTA2) with the core histone deacetylase complex. Source: Recombinant protein corresponding to aa1-291 from human MBD3, fused to His-tag at N-terminal expressed in E. coli. Molecular Weight: ~35.2kD (314aa) AA |
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| Size | 50ug, 250ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | n/a |
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| Gene, Accession, CAS # | Accession: NP_003917 |
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| Catalog # | 351362 |
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| Order / More Info | MBD3, Recombinant, Human, aa1-291, His-Tag (Methyl-CpG-binding Domain protein 3) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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