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| Product Name | MCAM, Recombinant, Human, aa50-646, His-Tag (Cell Surface Glycoprotein MUC18) |
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| Description | Purity ~90% (SDS-PAGE). Plays a role in cell adhesion, and in cohesion of the endothelial monolayer at intercellular junctions in vascular tissue. Its expression may allow melanoma cells to interact with cellular elements of the vascular system, thereby enhancing hematogeneous tumor spread. Could be an adhesion molecule active in neural crest cells during embryonic development. Acts as surface receptor that triggers tyrosine phosphorylation of FYN and PTK2/FAK1, and a transient increase in the intracellular calcium concentration. Source: Recombinant protein corresponding to aa50-646 from human MCAM, fused to His-Tag at N-terminal, expressed in E. coli. Molecular Weight: ~70.7kD AA |
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| Size | 10ug, 50ug, 100ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | Cell surface glycoprotein P1H12 Melanoma cell adhesion molecule, Melanoma-associated antigen A32 Melanoma-associated antigen MUC18S-endo 1 endothelial-associated antigen, CD146 |
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| Gene, Accession, CAS # | SwissProt: P43121 |
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| Catalog # | 374163 |
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| Order / More Info | MCAM, Recombinant, Human, aa50-646, His-Tag (Cell Surface Glycoprotein MUC18) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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