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| Product Name | Matrix Metalloproteinase 3 Inhibitor Screening Kit, BioAssay™ (MMP3, MMP-3, Stromelysin-1, SL-1, STMY1, Transin-1) |
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| Description | The matrix metalloproteinase-3 (MMP-3, stromelysin-1) exhibits a number of activities that would make it a particularly good tumor promoter. Like several other MMPs, MMP-3 was first cloned and later recloned as a cancer-specific gene. In addition to degrading numerous extracellular matrix components, MMP-3 can activate gelatinase B, the collagenases and several serpin-type serine proteinase inhibitors. Moreover, it can release a number of cell surface molecules, including E-cadherin, a known contributor to cancer development. Sample Type: Test inhibitors for MMP-3 Intended Use: The kit provides a rapid, simple, sensitive, and reliable test suitable as a high throughput screening assay of MMP-3 inhibition. The kit can be used to screen inhibitors of MMP-3. Test Principle: MMP-3 Inhibitor Screening Assay Kit, MMP-3 hydrolyzes a specific FRET substrate to release the quenched fluorescent group Mca, which can be detected fluorometrically at Em/Ex = 325/393nm. Kit Components: MMP-3 Assay Bu |
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| Size | 100 tests |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | n/a |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | M2421-30A |
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| Order / More Info | Matrix Metalloproteinase 3 Inhibitor Screening Kit, BioAssay™ (MMP3, MMP-3, Stromelysin-1, SL-1, STMY1, Transin-1) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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