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| Product Name | PPA1, aa1-289, Recombinant, Human (Inorganic Pyrophosphatase) |
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| Description | Purity ~85% (SDS-PAGE). Inorganic Pyrophosphatases are enzymes that catalyze the hydrolysis of pyrophosphate to two phosphate ions (1). This reaction is highly exergonic, and is utilized in many biochemical pathways, such as DNA synthesis (2) and bone formation (3), to render reactions effectively irreversible (4, 5). Likewise, inorganic pyrophosphatases can be coupled to unfavorable biochemical reactions in order to drive these reactions to completion, such as in the synthesis of activated sulfur donor 3'-phosphoadenosine-5'-phosphosulfate (PAPS) (6). Two inorganic pyrophosphatases, i.e. PPA1 and PPA2, are found in humans. PPA1 is highly active on pyrophosphate and is ubiquitously expressed (7). Source: Recombinant corresponding to aa1-289 from human PPA1, fused with 6-His tag at C-terminal, expressed in E. coli. Molecular Weight: ~33kD Endotoxin Level: ≤1EU/1ug (LAL) Biological Activity: Measured by its ability to hydrolyze pyrophosphate. The specific activity is >50,000 pmoles/min/u |
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| Size | 10ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | n/a |
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| Gene, Accession, CAS # | SwissProt: Q15181 |
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| Catalog # | P9542-51G |
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| Order / More Info | PPA1, aa1-289, Recombinant, Human (Inorganic Pyrophosphatase) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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