| 产品详情 |
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| Product Name | PPAR-beta/delta Inverse Agonist |
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| Description | Purity ~98% (HPLC). A cell-permeable, diaryl sulfonamide inverse agonist that demonstrates selectivity for the ligand-binding domain of the PPAR beta/delta receptor (IC50=93nM). Enhances the interaction of the PPARb/d ligand-binding domain with the co-repressor, SMRT-ID2 (EC50=10nM). Down-regulates the peroxisome proliferator response elements (PPREs)-driven target gene, ANGPTL4. Inhibits PPARb/d- specific agonist-induced transcriptional activity in human myofibroblasts and mouse thioglycollate-elicited peritoneal macrophages. Formula: C19H26N2O5S2 Molecular Weight: 426.6 Solubility: DMSO |
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| Size | 10mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | PPAR-beta/delta Inverse Agonist (Methyl 3-(N-(4-(hexylamino)-2-methoxyphenyl)sulfamoyl)thiophene-2-carboxylate, ST247) |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | 217691 |
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| Order / More Info | PPAR-beta/delta Inverse Agonist from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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| 产品资料 |
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