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| Product Name | PPAR gamma Modulator, SR1664 |
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| Description | Purity ~92% (HPLC). A cell-permeable non-thiazolidinediones derivative that binds tightly to peroxisome proliferator-activated gamma (PPAR-g) receptor (Ki=29nM; IC50=80nM), but does not exhibit any transcriptional agonism. Unlike TZD compounds, it does not induce weight gain or diminish hematocrit. Shown to effectively block CDK-5-mediated phosphorylation of Ser273 of PPAR-gamma in adipose tissue. Supresses hepatic glucose production, reduces plasma free fatty acid levels, and improves insulin sensitivity of adipose tissue. Formula: C33H29N3O5 Molecular Weight: 547.6 Solubility: DMSO (50mg/ml) |
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| Size | 2mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | PPAR gamma Modulator, SR1664 ((S)-4'-((2,3-dimethyl-5-(1-(4-nitrophenyl)ethylcarbamoyl)-1H-indol-1-yl)methyl)biphenyl-2-carboxylic Acid) |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | 217689 |
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| Order / More Info | PPAR gamma Modulator, SR1664 from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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