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| Product Name | OSM, Recombinant, Human (Oncostatin M) |
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| Description | Purity ~95% (SDS-PAGE). Oncostatin M (OSM) is a growth and differentiation factor that participates in the regulation of neurogenesis, osteogenesis and hematopoiesis. Produced by activate T cells, monocytes and Kaposi's sarcoma cells, OSH can exert both stimulatory and inhibitory effects on cell proliferation. It stimulates the proliferation of fibroblasts, smooth muscle cells and Kaposi's sarcoma cells, but, inhibits the growth of some normal and tumor cell lines. It also promotes cytokine release (e.g. IL-6, GM-CSF and G-CSF) from endothelial cells, and enhances the expression of low-density lipoprotein receptor in hepatoma cells. OSM share several structural and functional characteristics with LIF, IL-6, and CNTF. Oncostatin M is expressed in human 293 cells as a monomeric glycoprotein with an apparent molecular mass of 30kD. This higher molecular mass is due to glycosylation and is not seen in the E. coli expressed form of this cytokine (22kD). Glycosylation contributes to stability in cell growth media a |
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| Size | 10ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | n/a |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | 369002 |
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| Order / More Info | OSM, Recombinant, Human (Oncostatin M) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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