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| Product Name | SIRT3, Recombinant, Human |
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| Description | Purity ~95% (SDS-PAGE). NAD-dependent deacetylase sirtuin-3, mitochondrial, also known as SIRT3, belongs to the sirtuin family of proteins. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have a range of molecular functions and have emerged as important proteins in aging, stress resistance and metabolic regulation. SIRT3 exhibits NAD+-dependent deacetylase activity in the mitochondria. Over-expression of SIRT3 results in increased levels of the mitochondrial uncoupling protein 1. SIRT3 protein levels are also elevated in certain breast cancers. Source: Recombinant human SIRT3 protein, fused to His-tag at N-terminus, expressed in E.coli. AA Sequence: MGSSHHHHHH SSGLVPRGSH MSDKGKLSLQ DVAELIRARA CQRVVVMVGA GISTPSGIPD FRSPGSGLYS NLQQYDLPYP EAIFELPFFF HNPKPFFTLA KELYPGNYKP NVTHYFLRLL HDKGLLLRLY TQNIDGLERV SGIPASKLVE AHGTFASATC TVCQRPFPGE DIRADVMADR VPRCPVCTGV VKPDIVFFGE PLPQRFLLHV VDFPMADLLL ILGTSLEVEP F |
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| Size | 50ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | SIRT3, Recombinant, Human (NAD-dependent Deacetylase Sirtuin-3, Mitochondrial, hSIRT3, SIR2-like Protein 3, SIR2L3) |
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| Gene, Accession, CAS # | Accession: NP_036371 |
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| Catalog # | S1013-88F6 |
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| Order / More Info | SIRT3, Recombinant, Human from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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