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| Product Name | SIRT7, Recombinant, Human, aa2-400, His-Tag |
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| Description | Purity ~85% (SDS-PAGE). The sirtuins represent a distinct class of trichostatin A-insensitive lysyl-deacetylases (class III HDACs) and have been shown to catalyze a reaction that couples lysine deacetylation to the formation of nicotinamide and O-acetyl-ADP-ribose from NAD+ and the abstracted acetyl group. There are seven human sirtuins, which have been designated SIRT1-SIRT7. Recently, SIRT7 has been shown to activate transcription by RNA polymerase I and deacetylate p53. SIRT7 prevents progressive functional deterioration of the heart, and is suggested to play an important role in regulation of stress responses and cell death in the heart. Source: Recombinant protein corresponding to aa2-400 from human SIRT7, fused to His-tag at N-terminal, expressed in E. coli. Molecular Weight: ~49.3kD (aa2-400, NT His-tag) |
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| Size | 20ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | SIRT7, Recombinant, Human, aa2-400, His-Tag (NAD-dependent Deacetylase 7, SIR2-like Protein 7, Sirtuin 7, SIR2L7, Silent Information Regulator 7) |
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| Gene, Accession, CAS # | SIRT7, Gene ID: 7799, SwissProt: Q9NRC8 |
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| Catalog # | 220271 |
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| Order / More Info | SIRT7, Recombinant, Human, aa2-400, His-Tag from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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