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| Product Name | SIRT1, Recombinant, Human, aa2-747, His-Tag (NAD-dependent Protein Deacetylase Sirtuin-1) |
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| Description | Purity ~90% (SDS-PAGE). Inhibited by nicotinamide. Activated by resveratrol (3,5,4'-trihydroxy-trans-stilbene), butein (3,4,2',4'-tetrahydroxychalcone), piceatannol (3,5,3',4'-tetrahydroxy-trans-stilbene), Isoliquiritigenin (4,2',4'-trihydroxychalcone), fisetin (3,7,3',4'-tetrahydroxyflavone) and quercetin (3,5,7,3',4'-pentahydroxyflavone). MAPK8/JNK1 and RPS19BP1/AROS act as positive regulators of deacetylation activity. Negatively regulated by CCAR2. Source: Recombinant protein corresponding to aa2-747 from human SIRT1, fused to His-Tag at N-terminal, expressed in E. coli. Molecular Weight: ~85.5kD AA |
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| Size | 10ug, 50ug, 100ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | Regulatory protein SIR2 homolog 1, SIR2-like protein 1, hSIR2, Cleaved into the following chain: SirtT1 75kD fragment, 75SirT1 |
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| Gene, Accession, CAS # | SwissProt: Q96EB6 |
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| Catalog # | 375305 |
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| Order / More Info | SIRT1, Recombinant, Human, aa2-747, His-Tag (NAD-dependent Protein Deacetylase Sirtuin-1) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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