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| Product Name | Sirtuin 2 (human) (IntraCellular) BioAssay™ ELISA Kit (Sirt2, SIR2-like Protein 2) |
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| Description | Sirtuins (Silent information regulators; SIRTs) deacetylate and/or ADP-ribosylate lysine residues of target proteins in an NAD+-dependent manner. Sirtuins are critical regulators of many cellular processes, including insulin secretion, the cell cycle and apoptosis. Sirtuins, in particular SIRT1, emerged as critical regulators of longevity and aging in several model organisms. Furthermore, a variety of age-associated diseases such as type 2 diabetes, obesity, osteoporosis, and Alzheimer's disease are associated with sirtuins. Selective inhibition of SIRT2 achieves neuroprotection and identifies SIRT2 to be a potential therapeutic avenue in Huntington's and Parkinson's disease. |
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| Size | 96 tests |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | Sirt2, SIR2-like Protein 2 |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | 45291 |
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| Order / More Info | Sirtuin 2 (human) (IntraCellular) BioAssay™ ELISA Kit (Sirt2, SIR2-like Protein 2) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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