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| Product Name | Oxidized ATP |
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| Description | Purity ~98% (HPLC). A 2',3'-dialdehyde derivative of ATP that is commonly used to affinity label nucleotide sites in enzymes. Acts as a specific, irreversible antagonist of P2Z/P2X7 purinergic receptors in J774 mouse macrophages. Does not affect P2g receptors. Inhibits inflammatory pain in arthritic rat model by blocking ATP action on P2X7 receptor in nerve terminals. Also shown to irreversibly block ATP-induced Ca2+ influx in lymphocytes (?100uM). O-ATP-treated mice display better preservation and lower rate of rejection of pancreatic islet grafts with reduced Th1 transcripts. Solubility: H2O Primary Target: P2X7 |
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| Size | 25mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | Oxidized ATP (oATP, Purinergic Receptor Antagonist, Oxidized ATP, Purinergic Receptor P2X7 Antagonist, Oxidized ATP, Purinergic Receptor Inhibitor, Oxidized ATP, O-ATP) |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | 217610 |
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| Order / More Info | Oxidized ATP from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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