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| Product Name | Cdc25 Inhibitor IV, NSC 95397 |
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| Description | Purity ~95% (HPLC). A cell-permeable, para-naphthoquinone that has been reported to inhibit protein tyrosine phosphatase activity, including Cdc25 dual specificity phosphatase (Ki=32nM, 96nM, and 40nM for Cdc25A, -B, and -C, respectively) and blocks G2M transition in murine carcinoma cells. In addition, it is shown to inhibit S100A4 binding to myosin-IIA via covalent modification of cysteine residues, Cys81 and Cys86, in the target binding cleft (IC50=1.8uM). It demonstrates inhibitory activity against S100A4-mediated depolymerization of myosin-IIA filaments. Formula: C14H14O4S2 Molecular Weight: 310.4 Solubility: DMSO (100mg/ml, clear red solution) |
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| Size | 10mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | Cdc25 Inhibitor IV, NSC 95397 (2,3-Bis(2-hydroxyethylthio)-1,4-naphthalenedione, PTP Inhibitor XXIX) |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | 217261 |
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| Order / More Info | Cdc25 Inhibitor IV, NSC 95397 from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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