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| Product Name | N,N-Dimethylsphingosine ((2S,3R,4E)-2-(Dimethylamino)-4-octadecene-1,3-diol) |
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| Description | Purity ~98% (HPLC). Competitive sphingosine kinase (SphK) inhibitor. Exhibits inhibitory activity in platelets and in cytosolic extracts from U937, Swiss 3T3 and PC12 cells. Selectively inhibits sphingosine phosphorylation; does not inhibit N-acylation, and displays no inhibitory effect on protein kinase C at concentrations that inhibit SphK. Increases the release of IL-1beta and MCP-1 in cultured astrocytes; thought to mediate mechanical allodynia via this mechanism. Sequence: C20H41NO2 Solubility: DMSO (~30mM) Molecular Weight: ~327.55 |
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| Size | 10mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | n/a |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | 145682 |
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| Order / More Info | N,N-Dimethylsphingosine ((2S,3R,4E)-2-(Dimethylamino)-4-octadecene-1,3-diol) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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