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JNK3, Recombinant, Human, GST-Tag (MAPK10; JNK3A, MGC50974, PRKM10, p493F12, p54bSAPK, FLJ12099, FLJ33785) from UNITED STATES BIOLOGICAL |
| 产品详情 |
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| Product Name | JNK3, Recombinant, Human, GST-Tag (MAPK10; JNK3A, MGC50974, PRKM10, p493F12, p54bSAPK, FLJ12099, FLJ33785) |
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| Description | Purified (~70-90%). JNK3 is a member of the c-Jun N-terminal kinases (JNKs) which are part of the mitogen-activated protein (MAP) kinase family, and regulate signal transduction in response to environmental stress. JNK3 phosphorylates various transcription factors such as ATF2, Elk-1 and members of the Jun family. Activation and nuclear localization of JNK3, a neuronal-specific isoform of JNK, has been associated with hypoxic and ischemic damage of CA1 neurons in the hippocampus. Knockout mice lacking JNK3 showed reduced apoptosis of hippocampal neurons and reduced seizure induced by kainic acid, a glutamate-receptor agonist. Source: Recombinant protein corresponding to human JNK3, fused to GST-Tag at N-terminal expressed in Insect cells. Molecular Weight: ~71kD Specific Activity: 35nmol/min/mg as per activity assay protocol. Endotoxin: <1EU/ug (LAL) |
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| Size | 10ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | n/a |
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| Gene, Accession, CAS # | Accession: NM_002753 |
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| Catalog # | 500194 |
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| Price | |
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| Order / More Info | JNK3, Recombinant, Human, GST-Tag (MAPK10; JNK3A, MGC50974, PRKM10, p493F12, p54bSAPK, FLJ12099, FLJ33785) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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