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| Product Name | JNK1, Unactive Recombinant protein |
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| Description | MW: ~70 kDa. Recombinant full-length mouse JNK1 was expressed in E. coli cells using an N-terminal GST tag.Scientific Background: JNK1 is a member of the MAP kinase group that is activated by dual phosphorylation at thr and tyr residues during exposure to stress such as UV irradiation. JNK1 binds to the c-Jun transactivation domain and phosphorylates it on Ser-63 and Ser-73 (1). JNK1 has been shown to play an important role in disease processes. Activation of JNK1 results in defec |
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| Size | 0.02 mg, 0.05 mg |
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| Concentration | n/a |
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| Applications | Kinase Assay, Western Blot (WB) |
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| Other Names | [JNK; JNK1; PRKM8; SAPK1; JNK1A2; JNK21B1/2] |
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| Gene, Accession, CAS # | JNK1, Gene ID: 26419, Accession: NP_057909.1 |
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| Catalog # | MBS515406 |
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| Order / More Info | JNK1, Unactive Recombinant protein from MYBIOSOURCE INC. |
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| Product Specific References | 1. Derijard, B. et al: JNK1: a protein kinase stimulated by UV light and Ha-Ras that binds and phosphorylates the c-Jun activation domain. Cell. 1994 Mar 25;76(6):1025-37. 2. Kolodziejczyk, S M. et al: Activation of JNK1 contributes to dystrophic muscle pathogenesis. Curr Biol. 2001 Aug 21;11(16):1278-82. |
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