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| Product Name | JNK2, Unactive Recombinant protein |
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| Description | MW: ~74 kDa. Purity >90%. Recombinant full-length rat JNK2 was expressed in E. coli cells using an N-terminal GST tag.Scientific Background: JNK2 is a member of the MAP kinase group that is activated by dual phosphorylation at thr and tyr residues during exposure to stress such as UV irradiation and treatment of cells with TNFα. JNK2 binds to the c-Jun transactivation domain and phosphorylates it on Ser-63 and Ser-73 (1). JNK2 has been shown to play an important role in dise |
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| Size | 0.02 mg, 0.05 mg |
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| Concentration | 0.2mg/ml |
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| Applications | Kinase Assay, Western Blot (WB) |
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| Other Names | [SAPK; MAPK9] |
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| Gene, Accession, CAS # | JNK2, Gene ID: 50658, Accession: NP_059018.1 |
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| Catalog # | MBS515085 |
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| Order / More Info | JNK2, Unactive Recombinant protein from MYBIOSOURCE INC. |
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| Product Specific References | 1. Sluss, H K. et al: Signal transduction by tumor necrosis factor mediated by JNK protein kinases. Mol Cell Biol. 1994 Dec;14(12):8376-84. 2. Vogel, V. et al: Cardiac hypertrophy in the Prague-hypertensive rat is associated with enhanced JNK2 but not ERK tissue activity. Kidney Blood Press Res. 2001;24(1):52-6. |
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