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| Product Name | WDR77, Recombinant, Human, aa1-312, His-Tag (Methylosome Protein 50) |
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| Description | Purity ~85% (SDS-PAGE). Non-catalytic component of the 20S PRMT5-containing methyltransferase complex, which modifies specific arginines to dimethylarginines in several spliceosomal Sm proteins and histones. This modification targets Sm proteins to the survival of motor neurons (SMN) complex for assbly into small nuclear ribonucleoprotein core particles. Might play a role in transcription regulation. The 20S PRMT5-containing methyltransferase complex also methylates the Piwi proteins (PIWIL1, PIWIL2 and PIWIL4), methylation of Piwi proteins being required for the interaction with Tudor domain-containing proteins and subsequent localization to the meiotic nuage. Source: Recombinant protein corresponding to aa1-312 from human WDR77, fused to His-SUMO-Tag at N-terminal, expressed in E. coli. Molecular Weight: ~49.5kD AA |
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| Size | 50ug, 100ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | n/a |
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| Gene, Accession, CAS # | SwissProt: Q9BQA1 |
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| Catalog # | 370826 |
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| Order / More Info | WDR77, Recombinant, Human, aa1-312, His-Tag (Methylosome Protein 50) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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