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| Product Name | WDR5, Recombinant, Human, His-Tag |
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| Description | Purified (~44%). WD-repeat protein 5 (WDR5, also designated BMP-2-induced gene 3 kb or BIG-3) belongs to the family of WD-40 repeat proteins, and is essential for vertebrate development, Hox gene activation and global H3K4 trimethylation. WDR5 is a conserved subunit of Trithorax (TRX) histone methyltransferase complexes that selectively binds to dimethylated Lys4 (K4me2) in Histone H3 to promote K4 trimethylation by TRX. It is expressed in osteoblasts, chondrocytes, osteocytes and marrow stromal cells. The WDR5 protein contains 7 WD-repeats, which may play a role in its function of accelerating osteoblast differentiation. Source: Recombinant corresponding to aa2-334 from human WDR5, fused to His-tag at N-terminal, expressed in Sf9 insect cells via a baculovirus expression system. Molecular Weight: ~37.5kD Applications: Suitable for use in the study of enzyme kinetics, screening inhibitors, and selectivity profiling. |
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| Size | 100ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | WDR5, Recombinant, Human, His-Tag (WD Repeat Domain 5, BIG3, BIG-3, BMP2-induced 3-kb Gene Protein, SWD3, WD Repeat-containing Protein 5) |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | 137400 |
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| Order / More Info | WDR5, Recombinant, Human, His-Tag from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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