| 产品详情 |
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| Product Name | PTP1B Inhibitor |
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| Description | Purity >98%. Protein tyrosine phosphatase 1B (PTP1B) has critical roles in cell signaling relevant to diabetes, obesity, and cancer. PTP1B inhibitor is a cell-permeable allosteric inhibitor of PTP1B (IC50 s = 4 and 8 µM for 403 and 298 residue PTP1B forms, respectively). It binds reversibly and non-competitively, altering the conformation of the catalytic pocket. PTP1B inhibitor selectively increases the phosphorylation of the insulin receptor, insulin receptor substrate 1, and Akt, mimicking the action of insulin. |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | 3-(3,5-dibromo-4-hydroxybenzoyl)-2-ethyl-N-[4-[(2-thiazolylamino)sulfonyl]phenyl]-6-benzofuransulfonamide, Protein Tyrosine Phosphatase 1B Inhibitor |
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| Gene, Accession, CAS # | CAS: 765317-72-4 |
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| Catalog # | LS-H9583 |
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| Order / More Info | PTP1B Inhibitor from LIFESPAN BIOSCIENCES INC. |
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| Product Specific References | n/a |
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