| 产品详情 |
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| Product Name | SN-38 Glucuronide |
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| Description | Purity >95%. SN-38 glucuronide is an inactive metabolite of irinotecan , which is a derivative of the alkaloid camptothecin . SN-38 glucuronide is formed by glucuronidation of SN-38 , the active metabolite of irinotecan, by UDP glucuronosyl transferase 1A1 (UGT1A1) and UGT1A7. It can also be formed in COS-7 cells by UGT1A1 and UGT1A10, which are both up-regulated in an irinotecan/SN-38-resistant cell line. |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | (4S)-4,11-diethyl-3,4,12,14-tetrahydro-4-hydroxy-3,14-dioxo-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinolin-9-yl-Beta-D-glucopyranosiduronic acid, SN-38G |
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| Gene, Accession, CAS # | CAS: 121080-63-5 |
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| Catalog # | LS-H9954 |
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| Price | |
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| Order / More Info | SN-38 Glucuronide from LIFESPAN BIOSCIENCES INC. |
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| Product Specific References | n/a |
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